Which included HMGB1 mRNA, CK-MBmax, and Tnmax, and found that HMGB1 mRNA remained significantly associated with adverse LV remodeling, independently of myocardial infarct size (β ± SD = 0.23 ± 0.11, p = 0.03). This evidence concerns the gene HMGB1 and myocardial infarction.