It was found that only relative expression of HMGB1 mRNA in PBMCs from patients with adverse LV remodeling was significantly higher than in patients without adverse LV remodeling six months following MI (0.046 ± 0.018 vs. 0.036 ± 0.013, p = 0.04) (Figure 2A). The gene discussed is HMGB1; the disease is myocardial infarction.