The aim was to analyze the relative expression levels of HMGB1, TGF-β1, BIRC3, ADAM17, CDKN1A, and FTO genes in patients six months after MI and to correlate changes in the LV echocardiographic parameters with these genes’ relative expression in peripheral blood mononuclear cells (PBMCs). This evidence concerns the gene TGFB1 and myocardial infarction.