The aim was to analyze the relative expression levels of HMGB1, TGF-β1, BIRC3, ADAM17, CDKN1A, and FTO genes in patients six months after MI and to correlate changes in the LV echocardiographic parameters with these genes’ relative expression in peripheral blood mononuclear cells (PBMCs). The gene discussed is ADAM17; the disease is myocardial infarction.