The exact role of TRPM1 in ON-bipolar cells interacting with other membrane proteins, like nictalopin and glutamate receptors, is complex [43,44], but it is now known that mutations in the human TRPM1 gene lead to autosomal recessive complete congenital stationary night blindness (CSNB; OMIM: 613216) [45]. This evidence concerns the gene TRPM1 and congenital stationary night blindness.