IGF1 and sarcopenia: In the GWAS Catalog database, we initially identified 7773 variants significantly associated (p ≤ 5 × 10−8) with various traits: 2777 for testosterone measurement, 1608 for lean body mass, 514 for IGF-1 measurement, 230 for hand grip strength, 167 for reaction time measurement, 75 for brisk walking, 69 for interleukin-6 measurement, 62 for muscle measurement, 20 for thigh muscle volume, 14 for cortisol measurement, 3 for myoglobin measurement, 3 for lower body strength measurement, and 1 for sarcopenia (Supplementary Table S1).