This report describes the case of a small-for-gestational-age (SGA) late-preterm infant (34 + 6 weeks gestational age) diagnosed with NDM due to chromosome 8 deletion syndrome involving the GATA4 gene, which is associated with exocrine pancreatic insufficiency and congenital heart disease (partial atrioventricular canal defect—CAVD—with pulmonary valve stenosis) [9]. This evidence concerns the gene GATA4 and congenital heart disease.