BAG3 and cardiomyopathy: In addition to the cell cycle proteins, BAG3 interacts with proteins in a number of gene sets downregulated in cardiomyopathies, including HALLMARK_APOPTOSIS, HALLMARK_HYPOXIA, HALLMARK_UV_RESPONSE_UP, HALLMARK_XENOBIOTIC_METABOLISM, HALLMARK_UNFOLDED_PROTEIN_RESPONSE, HALLMARK_PROTEIN_SECRETION, HALLMARK_COMPLEMENT, HALLMARK_TNFA_SIGNALING_VIA_NFKB, HALLMARK_MTORC1_SIGNALING, HALLMARK_ESTROGEN_RESPONSE_LATE, HALLMARK_PI3K_AKT_MTOR_SIGNALING, and HALLMARK_IL2_STAT5_SIGNALING.