A study assessing the correlation between the concentrations of several inflammatory biomarkers and clinical activity of SLE highlighted that elevated levels of IFN-α are statistically significantly correlated with the presence of aPL antibodies (p = 0.004) and high levels of anti-double-stranded DNA (p = 0.004) [104]. The gene discussed is IFNA1; the disease is systemic lupus erythematosus.