PPA2 and heart failure: The NDUFA6 p.Ile94LysfsTer44 variant has been reported in a patient with recurrent exertional rhabdomyolysis [43], and the C1QBP p.Thr40AsnfsTer45 and PPA2 p.Glu172Lys variants have been reported in autosomal recessive mitochondrial cardiomyopathies with heart failure and sudden cardiac death [44,45].