For example, the probiotic L. reuteri suppresses inflammation and restores epithelial barrier function in DSS-induced colitis by reducing the number of DC subsets, like CD11b+CD11c+ DC, which play a crucial role in producing inflammatory cytokines, preventing neutrophil recruitment, and enhancing the expression of tight junction proteins, such as zonula occludens (ZO-1), and heat shock proteins (HSPs), such as HSP70 and HSP25, in the colon [28]. The gene discussed is TJP1; the disease is colitis.