To determine the susceptibility of pancreatic cancer cell lines to PD-H, H3N-375/1TS and CVA21, we infected five human (AsPC-1, MIA Paca-2, Capan-1, Capan-2, BxPC-3) and two murine pancreatic (Beta-TC-3 and KPC) tumor cell lines with these viruses at MOI 0.01 to 25. The gene discussed is PDP1; the disease is neoplasm.