TLR8 and neoplasm: Gene expression profiles that compared upregulation of TGFB2 mRNA in tumor tissue revealed that TGFB2 was co-regulated with three (C1QA, HLA-F, and LGALS9) of these nine genes that also included mRNA expression levels of TGFB1, MRC1/CD206, TLR8, SPI1, C1QA, HLA-F, and LGALS9 in the cluster of genes (Figure 6B).