Sixteen of the macrophage markers were upregulated greater than 10-fold in the tumor compared to normal tissues: CCL18, MARCO, APOC1, CD68, HLA-DRA, HLA-DQB1, CD74, CCL5, HLA-DRB1, EGLN3, C1QA, LGALS9, HHLA2, HLA-F, TLR8, and SPI1 mRNA. The gene discussed is TLR8; the disease is neoplasm.