Gene expression mRNA level analysis exhibited significant upregulation of mRNA levels in tumor tissue: IFNAR1 (3.4-fold increase, p < 0.0001), IRF9 (4.2-fold increase, p < 0.0001), STAT1 (7.1-fold increase, p < 0.0001), and IFI27 (66.3-fold increase, p < 0.0001). The gene discussed is IFI27; the disease is neoplasm.