Pancreatic adenocarcinoma tumors exhibit increased levels of mRNA expression for components of the Transforming growth factor-β pathway (TGFB1/2/3, TGFBR1/2/3) and Interferon Type I pathways (IFNAR1, STAT1, IRF9 and IFI27). The gene discussed is STAT1; the disease is pancreatic adenocarcinoma.