We have hypothesized as such that the function of TGFB2 expression is correlated with Interferon Alpha 1 (IFN-α), possibly through Interferon Regulatory Factor 9 (IRF9) mRNA as a key factor for eliciting the tumorigenic activity of IFN-α, and other members of the STAT family, and targeting these molecules simultaneously can help find more treatment options for pancreatic cancer. Here, IFNA1 is linked to familial pancreatic carcinoma.