Immp2l Deficiency Induced Granulosa Cell Senescence Through STAT1/ATF4 Mediated UPRmt and STAT1/(ATF4)/HIF1α/BNIP3 Mediated Mitophagy: Prevented by Enocyanin. The gene discussed is HIF1A; the disease is hyperinsulinemic hypoglycemia, familial, 4.