The expression of α-SMA, Laminin, and VEGF, as shown in the MetS group and the MetS + OVX group, significantly declined as compared with the control group (α-SMA: F (6, 35) = 22.7660, p < 0.0001; Laminin: F (6, 35) =11.1900, p < 0.0001; VEGF: F (6, 35) = 49.9328, p < 0.0001). The gene discussed is ACTA1; the disease is metabolic syndrome.