Increased fetal demise, cerebral microbleeds, and elevated levels of pro-inflammatory cytokines, such as IL-1β, IL-6, and IL-18, alongside a decrease in microglial density in the subventricular zone, are observed in a preeclampsia rat model, which suggests that preeclampsia leads to microvascular dysfunction, neuroinflammation, and reduced microglial presence in critical brain areas [76]. Here, IL1B is linked to preeclampsia.