The TLR-2 expression intensity (Supplementary Figure S4A) showed that COVID-19 patients with the C allele showed high TLR-2 expression compared with patients’ carriers of TT genotypes (rs3804099 and rs3804100) in naïve active B cells (p = 0.0485) (Supplementary Figure S4B). Here, TLR2 is linked to COVID-19.