Finally, CXCL8, a chemokine responsible for neutrophil recruitment, is also associated with Th17 immune responses; Th17 cells produce IL-17A, which can induce the production of CXCL8, and both cytokines have been observed as elevated in asthma and other inflammatory diseases, suggesting they could promote the sustained pro-inflammatory microenvironment [23]. The gene discussed is IL17A; the disease is asthma.