Furthermore, exosomal miR-146a and miR-155 were found to promote C-X-C motif chemokine receptor 7 (CXCR7)-mediated CRC metastasis by increasing the levels of the inflammatory cytokines interleukin-6, tumour necrosis factor-α, transforming growth factor-β, and CXCL12 [250]. This evidence concerns the gene IL6 and colorectal carcinoma.