Similarly, the H3K27ac-mediated activation of long intergenic non-protein coding RNA 519 (LINC00519) lncRNA was reported to promote lung squamous cell carcinoma (LSCC) progression by sponging miR-450b-5p and miR-515-5p to upregulate Yes-associated protein 1 (YAP1; transcriptional regulator) and enhance LSCC growth and metastasis [65]. The gene discussed is YAP1; the disease is squamous cell lung carcinoma.