BAX and non-small cell lung carcinoma: On the other hand, Glo2, specifically the mitochondrial isoform, appears to be linked to the promotion of mitochondrial apoptosis in human non-small cell lung cancer (NSCLC) A549 cells, upon oleuropein exposure, through a pathway involving multiple steps and inducing the upregulation of mitochondrial Glo2, which interacts with the pro-apoptotic protein Bax, thus, activating apoptosis [12].