Additionally, those metabolites were involved in 14 pathways of 2-oxocarboxylic acid metabolism, ABC transporters, alanine, aspartate and glutamate metabolism, aminoacyl-tRNA biosynthesis, beta-alanine metabolism, biosynthesis of amino acids, carbon metabolism, central carbon metabolism in cancer, glyoxylate and dicarboxylate metabolism, mineral absorption, pantothenate and CoA biosynthesis, protein digestion and absorption, valine, leucine and isoleucine biosynthesis, glycine, serine, and threonine metabolism. This evidence concerns the gene ABCG2 and cancer.