These pathways include central carbon metabolism in cancer, protein digestion and absorption, biosynthesis of amino acids, glyoxylate and dicarboxylate metabolism, pantothenate and CoA biosynthesis, citrate cycle (TCA cycle), carbon metabolism, valine, leucine and isoleucine biosynthesis, glycine, serine and threonine metabolism, aminoacyl-tRNA biosynthesis, 2-oxocarboxylic acid metabolism, alanine, aspartate and glutamate metabolism, mineral absorption, ABC transporters, and beta-alanine metabolism (Figure 2F). The gene discussed is ABCG2; the disease is cancer.