For example, transforming growth factor β (TGFβ) produced by platelets activates the epithelial-to-mesenchymal transition through the TGFβ/suppressor of mothers against decapentaplegic (SMAD) and nuclear factor-κB (NF-κB) pathways, which have direct effects on tumor growth [11]. Here, TGFB1 is linked to neoplasm.