Glutaminolysis also emerges as a critical pathway, with cancer cells demonstrating a heightened reliance on glutamine, facilitated by transporters such as the Alanine, Serine, Cysteine transporter 2 (ASCT2) and catalyzed by the upregulation of glutaminases—a type of reprogramming observed in various cancers including prostate cancer [30,31,32]. This evidence concerns the gene GLS and cancer.