TNF and Anorexia: Previous findings support a relationship between tumor-induced systemic inflammation and the progression of sarcopenia, particularly through proinflammatory cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-α), which contribute to anorexia, skeletal muscle proteolysis, metabolic disturbances, and cancer cachexia [23,24,25].