MYC and small cell lung carcinoma: Multiple studies have shown that high levels of MYC family proteins promote chemoresistance in SCLC both in vitro and in vivo [17,115,117,147,148,149], though MYC—and other classic oncogenes like RAS and Raf proto-oncogene (RAF)—were not found to confer radioresistance in SCLC [150].