Moreover, comparison of GATA4 and 6 expression in staged gastroesophageal tumors revealed statistically significant upregulation for both transcripts compared to normal biopsies (Figure 1B, Supplementary Table S2), an observation that is consistent with the elevated levels of both GATA4 and 6 proteins in gastric tumors based on the Human Protein Atlas (Figure 1C). Here, GATA4 is linked to gastric neoplasm.