HP and acute respiratory distress syndrome: The ROC curve analyses showed that sNOX2-dp, LPS, zonulin, albumin, and D-dimer predicted ARDS, with LPS showing the highest AUC (AUC for LPS: 0.760; 95% CI: 0.690–0.821; AUC for NOX2: 0.645; 95% CI: 0.562–0.728; AUC for zonulin: 0.675; 95% CI: 0.600–0.744; AUC for albumin 0.701; 95% CI: 0.627–0.767; AUC for D-dimer 0.685; 95% CI: 0.610–0.753) (Figure 3A–E).