The characterization and utilization of oxidative stress indicators, including MPO [22,23,25,26,27,28,29,70], PON [23,30,31,32,34,35,36,37,38,39,40], SIRT [41,42,43,44,45,46,47,48,49,50,51], SOD [38,52,53,54,55,56,57,58], and CAT [38,59,60,61,62,63,64,65] provide novel understanding of the development of psoriasis. The gene discussed is MPO; the disease is psoriasis.