We identified a significant increase in GCLC and Txnrd1 co-expression in brain cancer tissue (Pearson R = 0.44, padj = 1.28 × 10−5) compared to normal brain tissue (Pearson R = 0.25, padj = 3.41 × 10−5) (Figure 3b). The gene discussed is TXNRD1; the disease is brain cancer.