TP53 and glioblastoma: Combining Au with L-BSO demonstrated synergistic short-term and long-term cytotoxicity irrespective of p53 status in both wtp53 (U87MG GBM cell line, OPK161, OPK49 and isogenic OPK49 shRNA knockdown for P53 GSCs) and mutp53 (T98G GBM cell line and OPK257 GSC).