This in vivo result adds compelling evidence that both the significance/distribution of Ah-type afferents [2,14,16,18,21] and their inputs play a critical role in baroreflex afferent function, showing substantial sensitization to sexual-dimorphism-related conditions such as hypertension [32,33], asthma [34,35,36], silent angina [37,38], and others. Here, LIPH is linked to hypertensive disorder.