While phosphorylated NFκB levels were not significantly decreased, there was a reduction in the P-NFκB/NFκB ratios following treatments with (+)-Pinoresinol, Resveratrol, Bisdemethoxycurcumin, Pinosylvin, Methyl P-Hydroxycinnamate, and cis-Pterostilbene in both control and HGPS groups, indicating a tendency towards decreased P-NFκB levels, particularly in HGPS cells treated with Resveratrol, Bisdemethoxycurcumin, Methyl P-Hydroxycinnamate, cis-Pterostilbene, and (+)-Gallocatechin (Figure 6G,H). The gene discussed is NFKB1; the disease is Hutchinson-Gilford progeria syndrome.