VDAC1 and neoplasm: In tumors treated with si-hVDAC1, there was a notable increase in the expression of acetyltransferases lysine acetyltransferase 2A, 5, and 7 (KAT2A, 5, 7), while the expression of acetyltransferase KAT2B, which promotes cell proliferation and transcriptional activation, and deacetylase HDAC2, which is linked to tumor de-differentiation and invasion, was highly reduced [122].