Pérez-Losada J et al. [31] transfected the FUS::DDIT3 gene into the mouse genome and observed an elevated expression of FUS::DDIT3 and most of the symptoms of MLS, confirming that FUS::DDIT3 overexpression is a determinant of MLS in humans. Here, DDIT3 is linked to McLeod neuroacanthocytosis syndrome.