OLR1 and Leigh syndrome: An increased level of oxidized low-density lipoprotein (LDL) is clinically involved in the pathogenesis of atherosclerosis, and in LF tissues from LSS patients, lectin-type oxidized LDL receptor 1 (LOX-1) expression is higher than that in non-LSS patients, suggesting the active LDL/LOX-1 system in HLF [165].