UGCG and cardiac hypertrophy: Inhibition of B4GalT5 improved mitochondrial ROS levels, even after UGCG overexpression, suggesting an involvement mediated by ERK signaling, i.e., the activation of the UGCG-B4GalT5 axis was correlated with ERK activation, and the downregulation of UGCG reduced ERK activation and myocardial hypertrophy [70].