To further demonstrate the link between the three transcriptional regulators: MYC, EZH2 and YAP/TAZ and the tumor suppressor PTEN, we downloaded a list of transcripts and proteins positively or negatively correlated to PTEN in LUAD patients from the lung adenocarcinoma TCGA, Firehose Legacy study (Table S2). Here, MYC is linked to lung adenocarcinoma.