Interestingly, MYC depletion or inhibition by MYCi975 also increased the expression of YAP and TAZ targets in H1299, H1975 and H358 cells (Fig. 3F, G, S4D, E, S11D, E, S13E, S14A) consistent with previous reports in liver and breast cancer models [24, 34]. Here, MYC is linked to breast carcinoma.