In order to explore the distribution, expression and prognostic characteristics of different types of immune cells in different immune subtypes of glioma (S3 Table); Kaplan-Meier survival curve analysis and cluster analysis showed that B lineage, Myeloid dendritic cells, Neutrophils and CD8 T cells were used as prognostic risk factors in the CGGA database, while Cytotoxic lymphocytes and Monocytic lineage were used as prognostic protective factors (Fig 3C). This evidence concerns the gene CD8A and glioma.