In order to explore the characteristics of the immune microenvironment in gliomas, firstly, we selected 122 immune related metagene clusters (S1 Table), which represent eight different types of immune cells (including B lineage, CD8 T cells, Cytotoxic lymphocytes, Monocytic lineage, Myeloid dendritic cells, Neutrophils, NK cells and T cells). This evidence concerns the gene CD8A and central nervous system cancer.