In order to prevent tumor cells from growing, Raimondo et al. showed that EVs in citrus lemon juice could induce the expression of TNF‐related apoptosis‐inducing ligand (TRAIL), increase the expression of pro‐apoptotic genes (Bad and Bax), and decrease the expression of anti‐apoptotic genes (Survivin and Bcl‐xl). Here, BAX is linked to neoplasm.