ADA and Chediak-Higashi syndrome: By contrast, levels of lysosomal trafficking regulator (LYST), adaptor related protein complex 3 subunit beta 1 (AP3B1), and adenosine deaminase (ADA) in patients with Chédiak-Higashi syndrome (CHS), HPS type 2, and ADA deficiency, respectively, did not differ significantly from those in control samples (Fig. 4J–L).