POSTN and systemic sclerosis: Elevated levels of periostin have been associated with certain types of cancers (Ratajczak-Wielgomas and Dziegiel 2015), lung diseases, such as idiopathic pulmonary fibrosis (Uchida et al. 2012) and asthma (Jia et al. 2012), and skin diseases, such as atopic dermatitis (AD) and systemic sclerosis (SSc).