Of relevance to the role of HSPs in human malaria pathogenesis, transcripts for HSP60 (HSPD1) were down-regulated in SMA (log2FC = −0.81), as were HSP70 family members: HSPA1A (−1.31), HSPA1B (−0.99), HSPA4 (−0.33), HSPA4L (−0.68), HSPA5 (−0.51), and HSPA6 (−0.81). The gene discussed is HSPA4L; the disease is malaria.