Correspondingly, the percent parasitemia of iRBCs containing healthy single parasites was increased in the p47phox-/- mice compared to C57BL/6 mice (29.3 ± 5.8 vs. 13.9 ± 4.5, p47phox-/- vs. C57BL/6, day 8 p.i., p = 0.03). This evidence concerns the gene NCF1 and parasitic infectious disease.