Post hoc analysis of 594 participants with advanced DKD from the RE-GARDS study also examined other markers of inflammation/fibrosis than TNFR-1 and TNFR-2, namely chitinase 3-like 1 (YKL-40), MCP-1, and soluble urokinase-type plasminogen activator receptor (suPAR). This evidence concerns the gene TNFRSF1B and diabetic kidney disease.