TXN and carcinoma of the ampulla of vater: In the distal bile duct/ampullary carcinoma cohort, cytoplasmic Trx protein expression was significantly correlated with nuclear Trx (r = 0.653, p < 0.001), cytoplasmic TrxR (r = 0.436, p < 0.001), and nuclear TrxR (r = 0.328, p < 0.001) protein expression.