Trk and NTRK overexpression has been associated with clinicopathological features, metastasis, and lymphovascular invasion, as well as with poor prognosis of many neoplasms, including OSCC, through diverse methodological approaches [29,30,45,46,47,48]; however, this is the first time that the gene NTRK family was analyzed for OSCC. This evidence concerns the gene NTRK1 and neoplasm.