Impairment in the Wnt pathway has been associated with various psychiatric disorders in humans, such as WNT1, WNT2, and WNT7A in autism spectrum disorder [43], WNT7B and LRP5 in SCZ [44], and LRP5 and LRP6 in attention-deficit/hyperactivity disorder [45]. This evidence concerns the gene WNT1 and attention deficit-hyperactivity disorder.