HMGCR and metabolic dysfunction-associated steatotic liver disease: A study by Bur and colleagues suggested that tyrosol-containing olive leaf extracts may counteract or delay the complications of NAFLD by preventing the accumulation of lipids in hepatocytes, oxidative damage, and mitochondrial dysfunction and exerting a hypocholesterolemic effect due to the inhibition of 3-hydroxy 3-methylglutaryl coenzyme A reductase (HMG-CoA reductase) activity [60].