HNRNPA1 and frontotemporal dementia: Dysfunctional RBPs, like heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1), which is highly enriched in neurons, have been associated with neurodegenerative diseases of the central nervous system (CNS), including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and multiple sclerosis (MS) [4,5,6,7].