These studies also found primary site [27,28], T stage [27,32], N stage [27,32], and metastasis of bone [27,28,30,32,33], brain [27,32,33], and lung [27,28,30,32,33] predictive of OS as well as multiple liver metastases [29], grade [28,30,32,33], AJCC N status [28], tumor size [28,30,32], histological type [28,30,33], chemotherapy [27,28,31,32,33], carcinoembryonic antigen (CEA) [28], poor differentiation [29,30], adenocarcinoma [30], and bilobar liver distribution [28]. Here, CEACAM5 is linked to neoplasm.