We found that a tissue section from a 10-week-old wild- type C57BL/6J mouse has 2.5% cardiac fibrosis (Figure 7A) relative to the 9.7% cardiac fibrosis observed in a 10-week-old desmoplakin-deficient mouse heart, which shows more visible fibrosis across the ventricles (Figure 7B). This evidence concerns the gene DSP and fibrosis.