Si Miao Formula (SMF) and Morinda citrifolia L. (M. citrifolia) fruit phenolic extract have shown protective effects on NAFLD by decreasing the fasting blood glucose (FBG) and the AUC values of the intraperitoneal glucose tolerance test (IPGTT) and the intraperitoneal insulin tolerance test (IPITT) in HFHS-fed mice. Here, INS is linked to metabolic dysfunction-associated steatotic liver disease.