We analyzed the chemokine signaling pathway of lymphoma and CH and identified 38 DEGs, including GNG4, CXCL14, CXCL9, GNG7, RASGRP2, CCR2, CCL11, ITK, GNG2, CCR6, CCL5, VAV2, PRKCD, CCL21, CCL17, CCL19, LYN, CCL22, GNB5, PRKCB, ADRBK2, CXCR3, CCR5, HCK, CSK, GNGT2, CXCR4, STAT1, CCR7, GRK6, ADCY7, CXCR5, PREX1, PIK3CD, RAC2, DOCK2, JAK3, and VAV1 (Supplementary S3). The gene discussed is CCL5; the disease is cyclic hematopoiesis.